Work
Smart Lids - automated phenomics system that use computer vision & AI to measure 20+ health metrics continuously at 100× data density and 20× lower cost compared to traditional methods.
DAEUS: Whole-body gene delivery
Multi-AAV gene delivery system that enables delivery to 80% of the body mass of adult animals.
In review
Gene therapy for Wolfram Syndrome II
Whole-body gene therapy for a deadly accelerated aging disease - caused by the loss of pro-longevity gene Cisd2.
In review
A new baccterial species re-engineered to biomanufacture 3D objects
New protocol built on the POROS AAVX resin to flexibly and rapidly purify divergent AAV serotypes with one workflow
A therapeutic implant using wirelessly powered light and genetically engineered light-sensitive cells to controllably produce therapeutic proteins inside the body
A method to directly edit blood stem cells inside the body using CRISPR and AAV
When did aging begin? What was the first organism to age?
Mapping out the evolution of longevity from the simplest models.